Identification of an octamer-binding site in the mouse kappa light-chain immunoglobulin enhancer.
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چکیده
منابع مشابه
An AP1 binding site upstream of the kappa immunoglobulin intron enhancer binds inducible factors and contributes to expression.
Expression of the kappa immunoglobulin light chain gene requires developmental- and tissue-specific regulation by trans-acting factors which interact with two distinct enhancer elements. A new protein-DNA interaction has been identified upstream of the intron enhancer, within the matrix-associated region of the J-C intron. The binding activity is greatly inducible in pre-B cells by bacterial li...
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An octamer-binding site is crucial for the activity of an enhancer active at the embryonic met-/mesencephalic junction
An enhancer sequence found in the Protease Nexin-1 (PN-1) gene was shown to drive lacZ expression specifically at the met-/mesencephalic junction in transgenic mouse embryos. A functional study of this enhancer has been performed to better understand the mechanisms regulating isthmic gene expression. An octamer-binding site for POU domain factors was found to be crucial for the activity of the ...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 1989
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.9.10.4239